If both male and female are virgins can they still get STIs?

In most cases, no. If neither of you has had any sexual contact with anyone else, there's no STI to pass between you.

STIs are transmitted from one person to another. They don't appear out of nowhere. If neither person has an infection, neither person can give one to the other.

There are a few exceptions though. Herpes can be passed through kissing if one of you has cold sores (cold sores are caused by the herpes virus). HPV can sometimes be transmitted through skin-to-skin contact in the genital area without penetrative sex. And some infections like HIV or hepatitis B can be passed from a mother to a baby during birth, which means someone could technically have an infection without ever having had sex.

But in the scenario you're describing, where two people who've never had any sexual contact have sex with each other for the first time, the risk of STIs is very low.

If both people are virgins and neither has had any sexual contact with anyone else, the risk of getting an STI is very low.

STIs are passed from one person to another. They do not appear out of nowhere. If neither person has an infection, neither can give one to the other.

There are a few small exceptions. Cold sores can be passed through kissing. Some infections like HIV can be passed from a mother to her baby during birth. But in most cases, two people who have never had sexual contact cannot give each other an STI.